Epigenetic Drug & Diagnostic Pipelines Now Available at ReportsandReports

Dallas, TX, October 29, 2010 --(PR.com)-- ReportsandReports announce Epigenetic Drug & Diagnostic Pipelines Market Research Report in its Store.

Browse complete Report at: Epigenetic Drug & Diagnostic Pipelines
http://www.reportsandreports.com/reports/34203-epigenetic-drug-diagnostic-pipelines.html

Report Summary
Epigenetics is a rapidly growing field with promising implications for treatment of cancer and potentially other diseases. Research interest in epigenetics has exploded in recent years, and considerable progress has been made in the commercialization of discoveries in this field.

Discussed in this Report:
Diagnostic applications of epigenetics
Diseases and conditions targeted by current and emerging epigenetic-based therapies
Companies marketing and/or developing therapies that target epigenetic changes within the disease process
Current and projected markets for epigenetic diagnostic and therapeutic products
Strategic issues and major challenges for developers of epigenetic-based products
Thought-leader interviews

Many companies have recognized the potential benefits of epigenetic-based diagnostic and therapeutic products. Two epigenetic tests for colorectal cancer screening are CE-marked and available in Europe, and a number of epigenetic tests are available through clinical laboratories in the United States as laboratory developed tests (LDTs). Four epigenetic drugs have now been approved by the US FDA.

The first mechanism of epigenetics to be widely studied was DNA methylation. Two of the approved epigenetic drugs are demethylating agents, and most of the epigenetic diagnostic activity to date has focused on methylation markers. A second major epigenetic mechanism is modification of histones by various enzymes, including histone deacetylases (HDACs).

The other two approved epigenetic drugs are HDAC inhibitors. In Chapter 2, Epigenetic Drug & Diagnostic Pipelines: DNA Methylation, HDAC Inhibitors, and Emerging New Targets provides an overview of epigenetics and its mechanisms, diagnostic methods to detect changes in DNA methylation, and epigenetic therapeutic targets.

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Original Source: Epigenetic Drug & Diagnostic Market
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