Dr. Masoud Toloue will Describe Methyl-Seq, PCR-Free and Small RNA-Seq NGS Library Prep Technologies

Austin, TX, June 30, 2011 --(PR.com)-- Dr. Masoud Toloue, Director of Genomic Research at Bioo Scientific, will describe the latest DNA and RNA library preparatory methods for next-generation sequencing at the upcoming European Next Generation Sequencing Congress in Hamburg, Germany. Strategies for massive parallel sequencing have revolutionized research across diverse scientific disciplines. Despite these advances, DNA and RNA sample preparations, one of the most important aspects of next generation sequencing, continue to use outdated, biased and cumbersome methods. However, recent improvements in library preparation technology have improved genome sequencing.

Bioo Scientific is commitment to developing innovative solutions to improve, simplify and reduce bottlenecks in next generation sequencing. Fragmentation, ligation and amplification methods typically used in next generation sequencing library preparation are susceptible to sequence bias, require significant preparatory time and are highly inefficient. In order for genomic sequencing to become a staple in the clinic, steps need to be taken to improve this. To circumvent these obstacles Bioo Scientific has developed several strategies for RNA–Seq that not only eliminate small RNA circularization and linker dimers, but also allow for cross genome analysis using multiplexed barcodes. Improvements to DNA preparations include a series of coordinated reactions designed to maximize ligation yield while not compromising on efficiency. This work has directly resulted in the development of a method to successfully prepare libraries without any PCR amplification, a crucial advance when seeking non biased data.

About Bioo Scientific Corporation
Bioo Scientific Corporation is an Austin, TX based biotechnology company that provides innovative solutions to the life science industry. Bioo Scientific offers a complete portfolio of products that increase sensitivity, flexibility and speed to next-generation sequencing.

Bioo Scientific’s products are used around the world and can be purchased both directly or through our global distribution network with markets in more than 40 countries. For more information about Bioo Scientific’s NGS product line, visit www.biooscientific.com.

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