Altogen Biosystems Develops Powerful In Vivo RNAi Research Tool for Oncology

Austin, TX, October 13, 2015 --(PR.com)-- Lipid-based liposomes of nanometer size are one of the most powerful molecules for delivery of novel therapeutics into target tissues enabling targeted cancer therapeutics. Pharma companies actively investigating new RNAi-based therapeutics where cargo molecules such as a small proteins, DNA, siRNA, and microRNA are studied for their gene silencing potential to fight cancer. Altogen Biosystems has developed a Lipid-Based In Vivo Transfection Kit that is functionally tested in both rats and mice and providing powerful research tool in the field of RNAi application for oncology drug discovery. The versatility and power of a lipid-based transfection reagent stems from the molecular structure of a lipid-based liposome condensed into 100 nm particles. Generally, a lipid-based structure contains a positively charged head and several hydrocarbon chains. This produces a molecule with cationic properties and the interaction between the charged head and nucleic acids or any negatively charged cargo creates complex protected from nucleases in vivo.

Lipid-based In Vivo Kit developed by Altogen Biosystems is a robust and effective tool for creating condensed transfection complexes. The proprietary formulation minimizes complex size and provides an effective method for delivery into target tissues. Furthermore, the formulation minimizes cargo degradation and there is no detectable inflammatory response. Another key advantage to Altogen Biosystem’s formulation is the possibility for tissue-targeting through mode of administration (intraperitoneal, intratumoral and systematic intravenous). Optimized protocols included in the kit guide research methods and allow for maximum delivery, sustained mRNA knockdown, and reproducible results.

Read more about the Lipid-Based In Vivo Transfection Kit at http://www.altogen.com/lipid-based-in-vivo-transfection-reagent.php.

As a leading provider of preclinical biology research products and services (offered by Altogen Labs, www.altogenlabs.com), Altogen Biosystems (www.altogen.com) ensures quality of all Altogen® In Vivo products.

Source: Altogen Biosystems, 848 Rainbow Blvd #823, Las Vegas, NV 89107.

Tel: (702)349-6103. Fax: (702) 989-0841. E-mail: techserv@altogen.com